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Table 2 The percentage of cells in different phases of life cycle after treatment with luteolin or quercetin

From: Luteolin, an Abundant Dietary Component is a Potent Anti-leishmanial Agent that Acts by Inducing Topoisomerase II-mediated Kinetoplast DNA Cleavage Leading to Apoptosis

  

M1 (sub G0/G1 or dead)

M2 (G0/G1)

Type of Cells

Incubated with

1d

3d

1d

3d

L. donovani

DMSO alone

1.0

10.0

54.0

55.0

promastigotes

Luteolin

1.0

32.0

60.0

39.0

 

Quercetin

1.0

26.0

59.0

46.0

 

DMSO alone (at 37°C)

1.0

33.0

68.0

42.0

PBMC blast

DMSO alone

 

8.0

 

79.0

 

Luteolin

 

7.0

 

80.0

 

Quercetin

 

7.0

 

84.0

  1. PBMC, peripheral blood mononuclear cells; DMSO, dimethysulfoxide.