Fig. 2
Scatter plots of the increase in free β-catenin levels in stable presenilin PSEN1 human embryonic kidney HEK 293 cells.
(A) Plot of the increase in free cytosolic b-catenin levels. The ratio of the amount of normalized cytosolic-free β-catenin after 1 hr of LiCl stimulation to the amount of normalized cytosolic-free β-catenin before LiCl stimulation (fold increase) of five independent experiments were plotted. (B) Plot of the increase in free nuclear β-catenin levels. The ratio of the amount of normalized nuclear-free β-catenin after 1 hr of LiCl stimulation to the amount of normalized nuclear-free β-catenin before LiCl stimulation (fold increase) of six independent experiments were plotted. Symbols: data points are plotted using black boxes (■); the black horizontal bar (—) indicates the median of each set of data. WT, wild type.