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Table 2 Peptide sequences of mycobacterial HSP65 epitope and the corresponding human HSP63 epitope, as recognized by CD4 + and CD8 + T-cell clones

From: T Cells Recognize an Immunodominant Epitope of Heat Shock Protein 65 in Kawasaki Disease

A

Origin of HSP65 Peptide

Amino Acid Sequence

Map Position

 

Mycobacterium Tuberculosis P1 antigen

YEKIGAELVKEVAKKTDDVAG YKNIGAKLVQDVANNTNEEAG

65–85 90–110

B

 

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  1. The sequences of mycobacterial HSP65 peptide 65–85 and of the corresponding human HSP63 90–110 peptide are shown. Identical residues are underlined in bold (A). The deduced CD4 and CD8 minimal epitope sequences from the mycobacterial HSP65 65–85 peptide also are shown. Identical residues with the corresponding human HSP63 90–110 peptide are underlined in bold (B). HSP65, heat shock protein 65.
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Molecular Medicine

ISSN: 1528-3658