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Fig. 3 | Molecular Medicine

Fig. 3

From: Chlamydia trachomatis Mouse Pneumonitis Lung Infection in IL-18 and IL-12 Knockout Mice: IL-12 Is Dominant over IL-18 for Protective Immunity

Fig. 3

Antigen-driven cytokine responses by spleen cells.

Spleen cells from mouse pneumonitis (MoPn)-infected interleukin (IL)-18 knockout (KO), IL-12 KO and wild type (WT) mice were cultured at 7.5 × 106 cells/ml with stimulation by heat-killed elementary bodies (EBs). Supernatants were harvested for IL-12 and IL-10 assays by ELISA. Data represented the mean ± standard deviation (SD) of results from 4 to 9 mice each group after 3 days in culture. * represents undetectable level of IL-12.

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Molecular Medicine

ISSN: 1528-3658