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Table 1 Splenic interferon (IFN)-γ production from mice intranasally infected with mouse pneumonitis (MoPn) (u/ml)a

From: Chlamydia trachomatis Mouse Pneumonitis Lung Infection in IL-18 and IL-12 Knockout Mice: IL-12 Is Dominant over IL-18 for Protective Immunity

 

Medium

HK-EB

HK-EB + rIL-18

HK-EB + rIL-12

HK-EB + anti-CD4

Wild type

<10

426 ± 85

3075 ± 1511

3345 ± 1511

16 ± 8

IL-18 KO

<10

139 ± 32b

2014 ± 446

2116 ± 742

18 ± 12

IL-12 KO

<10

16 ± 6b

30 ± 13b

2316 ± 1142

<10

  1. aValues are means ± standard deviations from 4 to 9 mice each group at 10 days postinfection. bSignificantly different (p < 0.05), compared with those in wild type (WT) mice. HK-EB, heat-killed elementary bodies; recombinant interleukin (rIL); IL, interleukin; KO, knockout.
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Molecular Medicine

ISSN: 1528-3658