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Fig. 6 | Molecular Medicine

Fig. 6

From: Transgenic Mice Bearing a Human Mutant Thyroid Hormone βl Receptor Manifest Thyroid Function Anomalies, Weight Reduction, and Hyperactivity

Fig. 6

Behavioral activity

(A) Nocturnal stereotypic activity counts over 30 min of hemizygous F2 mice of Family D (TG, n = 8, NTG, n = 11) (B) Daytime stereotypic activity counts over 60 min of Family D compared with Family A after LP. injection of saline placebo and high-dose methylphenidate. (C) Daytime total horizontal distance traveled over 60 min of Family D compared with Family A after LP. injection of saline placebo and high-dose methylphenidate. Values are given as mean ± SEM and statistical analysis performed using ANOVA where p < 0.05 was considered significant (StatView RII).

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Molecular Medicine

ISSN: 1528-3658