Fig. 2

Transcription and replication scheme of Bunyaviridae genome segments

The left panel shows the scheme for a negative-strand segment and the right panel that for an ambisense segment. The genome RNA (vRNA) and the positive-sense viral complementary RNA (vcRNA), also known as anti-genome or replicative intermediate RNA, are only found as ribonucleoprotein complexes and are encapsidated by N protein (●). The mRNA species contain host-derived primer sequences at their 5′ ends (■) and are truncated at the 3′ end relative to the vRNA template; the mRNAs are not polyadenylated.