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Table 2 Inhibition of P. falciparum FVO growth or invasion with anti-EBA-175 RII polyclonal sera in vitro

From: Induction of Biologically Active Antibodies in Mice, Rabbits, and Monkeys by Plasmodium falciparum EBA-175 Region II DNA vaccine

 

%Parasitemiab

  

Seraa

Controlc

Experimental

Inhibition (% of control)

Paired t-test

Mouse

0.82 ± 0.07

0.28 ± 0.08

66

<0.01

Rabbit

1.04 ± 0.20

0.59 ± 0.11

43

<0.05

  1. aPooled A/J sera and individual rabbit serum were tested at a dilution of 1:10 and 1:5, respectively for one cycle of invasion in suspension microcultures.
  2. bValues are means ± standard errors of triplicates.
  3. cControl sera were from mice or a rabbit immunized with empty vector (VR1020).
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Molecular Medicine

ISSN: 1528-3658