Fig. 2

Homozygosity for allele ADH3*2 of the alcohol dehydrogenase-3 gene is associated with ALD. The frequencies of the ADH3*2/ADH3*2 genotype (bars on the right side) and of the other two reciprocal genotypes (bars on the left side) are shown in healthy controls, ALD and cirrhotic patients all being homozygous for allele C1 of the cytochrome P450E1 gene. The numbers on top of each bar indicate the number of individuals with the indicated genotype out of the total individuals in that category. HD: heavy drinker individuals. ALD: ethanol-induced liver damage.