Fig. 3
From: Melanoma Differentiation Associated Gene-7 (mda-7): A Novel Anti-Tumor Gene for Cancer Gene Therapy
Ad-mda7-induced apoptosis and cell cycle regulation. (A) TUNEL assay: Microscopic illustration of Ad-mda7 infected MCF-7 cells undergoing apoptosis. Ad-CMVp(A) control is shown in the right panel. Apoptotic cells exhibit dark brown staining. (B) DLD-1 cells were infected with Ad-mda7 or Ad-luc and 48 hr later examined for Annexin V staining by FACS analysis. The percentage of positively stained cells is shown.