Table 2 Genomic analyses of mda-7 exons in tumor cells and normal blood PBL
From: Melanoma Differentiation Associated Gene-7 (mda-7): A Novel Anti-Tumor Gene for Cancer Gene Therapy
Cell Line | Origin | p53 Status | Exon 4 Polymorphism | Ad-mda7 Growth Inh. |
|---|---|---|---|---|
A549 | NSCLC | wt | C/T | + |
H1299 | NSCLC | null | C/T | + |
DLD-1 | Colorectal | mut | C/C | + |
PC-3 | Prostate | null | C/C | + |
HeLa | Cervical | wt | C/T | + |
PBL | Normal | wt | C/C | n.d.1 |
(n = 5) | blood | Â | Â | Â |
PBL | Normal | wt | C/T | n.d. |
(n = 3) | blood | Â | Â | Â |
PBL | Normal | wt | T/T | n.d. |
(n = 2) | blood | Â | Â | Â |