Skip to main content
Fig. 7 | Molecular Medicine

Fig. 7

From: Species-Crossreactive scFv Against the Tumor Stroma Marker “Fibroblast Activation Protein” Selected by Phage Display From an Immunized FAP−/− Knock-Out Mouse

Fig. 7

Immunohistochemical detection of MB MO36 epitopes in human cancer. (A, B) Breast carcinoma. (C) Ovarian carcinoma. (D) Xenograft from the breast carcinoma cell line ZR75.1 in an NMRI nu/nu mouse. Fresh frozen sections were incubated with MB MO36 (A, C, D) or, as a negative control, without minibody (B). Detection on samples A and B was done with an anti-c-myc antibody followed by biotinylated horse anti-mouse IgG and the avidin-biotin complex immunoperoxidase procedure. On samples C and D, biotinylated goat antihuman IgG and the avidin-biotin complex immunoperoxidase procedure were used. Counterstaining was done with Harris’ hematoxylin.

Back to article page

Molecular Medicine

ISSN: 1528-3658