Fig. 3
From: Keratocan Expression Is Increased in the Stroma of Keratoconus Corneas
Immunostaining for keratocan in the corneal stroma. Sections were from a 16-year-old normal individual (A and B), two patients with keratoconus (C, 29-year-old, and D, 67-year-old), an 84-year-old patient with aphakic bullous keratopathy (E), and a 69-year-old patient with corneal scar (F). Sections were immunostained with an antibody against keratocan (A, C, D, E, and F) or normal rabbit IgG (B, negative control). Positive staining appears as brown deposits in both keratocytes and stromal matrices. Note the increased staining in keratoconus specimens (original magnification, ×40).