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Table 2 Relative quantitative RT-PCR for keratocan.

From: Keratocan Expression Is Increased in the Stroma of Keratoconus Corneas

Sample

Keratocan/18S Ribosomal RNA Ratio

Mean ± SD

Normal human

  

20y

0.84

 

22y

0.72

 

35y

0.61

 

45y

0.67

 

54y

0.70

0.71 ± 0.08

Keratoconus

  

25y

0.98

 

34y

1.19

 

36y

1.10

 

45y

1.11

 

62y

1.81

1.24 ± 0.33*

Fuchs’

  

51y

0.67

 

80y

0.60

0.64 ± 0.05

PBK

  

68y

0.44

 

86y

0.61

0.52 ± 0.12

Scar

  

36y

0.71

0.71

  1. *p < 0.008.
  2. Fuchs’, Fuchs’ corneal dystophy; PBK, pseudophakic bullous keratopathy; y, age of patients in years.
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Molecular Medicine

ISSN: 1528-3658