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Table 3 Summary of published reports on the association between heterozygosity for CCR5-Δ32 chemokine receptor allele and the risk of MTCT of HIV-1 or the rate of disease progression

From: Genetic Determinants of Pediatric HIV-1 Infection: Vertical Transmission and Disease Progression Among Children

 

Risk Factor

Population

(n) Patients

Risk of MTCT

Rate of HIV progression

Reference

African American

144

None

None

52

Argentinean

886

None

None

28,53

Austrian

79

↓

NS

20

French

512

None

↓

25

Mixed American

122

None

NS

54

Mixed American

831

None

NS

55

Mixed American

457

NS

↓

26

Mixed American

41

NS

↓

27

Spaniard

73

None

None

38

  1. NS, not studied; ↓, decreased.