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Table 2 Cross-reactivity pattern of rheumatoid factors

From: VH3-21 B Cells Escape from a State of Tolerance in Rheumatoid Arthritis and Secrete Rheumatoid Factor

No. of Clones Antibody Reactivity
IgG Fc Actin Keratin ssDNA Thyroglobulin Tetanus Toxoid
2 + + + + + +
1 + + + + +
1 + + + +
1 + + + +
1 + + + +
1 + + + +
1 + + +
1 + +
4 + +
3 + +
3 + +
4 + +
45 +