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Table 3 VH gene segment usage in IgM heavy chains from RF + and RF B cells

From: VH3-21 B Cells Escape from a State of Tolerance in Rheumatoid Arthritis and Secrete Rheumatoid Factor

Donors Specificity No. of Clones Frequency (%) p Patients Versus Normal Controls
VH1 VH2 VH3 VH4 VH5 VH6
Normal controls RF 127 30.7 3.9 42.5 8.7 12.6 1.6 N/A
RA patients RF 113 23.0 3.5 50.4 16.8 4.4 1.8 NS
  RF+ 60 13.3 1.7 76.7 3.3 3.3 1.7 0.001
pSS patients RF 82 24.4 2.4 43.9 12.2 11.0 6.1 NS
  RF+ 47 21.3 2.1 61.7 6.4 4.3 4.3 NS