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Table 4 Usage of VH3 gene segment subtypes in IgM heavy chains from RF + and RF B cells

From: VH3-21 B Cells Escape from a State of Tolerance in Rheumatoid Arthritis and Secrete Rheumatoid Factor

    Frequency (%)  
Donors Specificity No. of Clones V3-23 V3-30 V3-21 V3-15 Others p Patients Versus Normal Controls
Normal controls RF 33 39.4 27.3 0.0 3.0 30.3 N/A
RA patients RF 34 17.6 20.6 5.9 8.8 47.1 NS
  RF+ 31 16.1 13.0 19.4 16.1 35.5 0.007
pSS patients RF 27 18.5 25.9 7.7 3.7 44.4 NS
  RF+ 27 11.1 37.0 14.8 0.0 37.0 0.03