Fig. 3

Sequences of CDR3 intervals of RA synovial sequences. (A) Nucleotide sequences are compared with germline V_H, D_H, or J_H gene segments when assignable; dots indicate sequence homology. Base changes in the putative D_H gene segments are shown in lower case letters, † = clones previously reported (20). P or N nucleotides and D_H reading frames are also shown. Phil = hydrophilic, Stop = termination, Phob = hydrophobic, Inv = inverted (14). (B) Deduced amino acid sequences, † = clones previously reported; * = end of transcript.