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Table 2 The parameters for [ 3 H]paroxetine binding to the hippocampal 5-HTT in schizophrenic and control subjects separated according to 5-HTTLPR genotype

From: No Association between the Serotonin Transporter-Linked Promoter Region Polymorphism and Either Schizophrenia or Density of the Serotonin Transporter in Human Hippocampus

 

Schizophrenic

Nonschizophrenic

 

n

Kda

B max b

n

Kda

B max b

L/L

11

0.59 ± 0.07

164 ± 20

13

0.25 ± 0.03

127 ± 19

L/S

16

0.42 ± 0.05

153 ± 11

18

0.24 ± 0.02

144 ± 10

s/s

11

0.40 ± 0.05

146 ± 17

10

0.27 ± 0.03

150 ± 17

  1. a nM.
  2. b fmol/mg protein.
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Molecular Medicine

ISSN: 1528-3658