Fig. 1
From: Activator Protein-1 Mediates Induced but not Basal Epidermal Growth Factor Receptor Gene Expression
API can bind to multiple sites in the EGFR promoter. (A) DNase I footprinting was performed using 1 and 2 footprint units of purified proteins (AP1, TFIID, Sp1 and AP2 as shown above each lane) and the end-labeled EGFR promoter fragment −16 to −734. AP1 footprints are indicated on the left of the figure. (B) DNase I foot-printing was performed using 1 and 2 footprint units of AP1 and the EGFR promoter fragment −1109 to −735. AP1 footprints are indicated on the left of the figure.