Table 1 Clinical characteristics and serum and renal AGE parameters of donors of fresh PBMN

Subjects (n)

7

11

18

Sex (M/F)

6/1

4/7

10/8

Age (years)

43 ± 11

37 ± 10

47 ± 13

HbAlc (%)

5.3 ± 0.4

7.8 ± 1.6^*

8.6 ± 0.8^*

Serum AGEs (U/mL)

2.5 ± 1.6

6.0 ± 3.4^*

8.0 ± 3.6^*§

Urine AGEs (U × 10³/mL)

175 ± 70

256 ± 66^*

153 ± 55

Total cholesterol (mg/dL)

208 ± 46

194 ± 29

226 ± 44

Triglycerides (mg/dL)

106 ± 51

83 ± 54

140 ± 55^§

Creatinine (mg/dL)

0.81 ± 0.15

0.80 ± 0.12

0.98 ± 0.26

UAER (ug/min)

4.1 ± 1.1

4.1 ± 1.1

851 ± 75^**

Ccr (mL/min)

105 ± 33

106 ± 17

87 ± 30

C_AGE (U × 10³/min)

3.0 ± 0.18

4.42^* ± 0.26

2.16^** ± 0.12