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Fig. 2 | Molecular Medicine

Fig. 2

From: Identification by mRNA Differential Display of Two Up-regulated Genes as Candidate Mediators of AIDS Dementia

Fig. 2

Reverse Northern analysis confirming alternate gene regulation patterns for three differential display bands identified as TIFIIB, HOHO1, and TrkB by nucleotide sequence analysis. DNA slot blots prepared with the three fragments were probed with cDNAs derived from the cortex of SNCs and from HIV-1 infected patients with ND or SD (MSK 3 or 4). Consistent with differential display RT-PCR reverse Northern analysis demonstrates down-regulation of TIFIIB and up-regulation of HOHO1 and TrkB in brain tissue samples from AIDS patients with SD as compared to AIDS patients with ND and SNCs.

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Molecular Medicine

ISSN: 1528-3658