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Fig. 6 | Molecular Medicine

Fig. 6

From: Presence of DNA Fragmentation and Lack of Neuroprotective Effect in DFF45 Knockout Mice Subjected to Traumatic Brain Injury

Fig. 6

DNA cleavage in isolated nuclei (A) and plasmid DNA (B) induced by cytosolic extracts from sham control (0 hr) and injured rat cortex (24 and 72 hr). Cytosolic extracts from injured brain tissues were isolated at indicated times after TBI. Nuclei from rat normal cerebellum or pCR2.1 plasmid DNA were incubated with extracts, and DNA was analyzed by agarose gel electrophoresis, as described in Materials and Methods. Data are representative of tens of experiments with similar results. The standard DNA fragments (M) represent a 1-kb DNA ladder.

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Molecular Medicine

ISSN: 1528-3658