Fig. 4

Cerebral infarct volume is similar in HO1^−/− and wild-type (WT) mice following MCAO. Mice were subjected to 1 hr MCAO and 23 hr reperfusion. The infarct volume shown on the histogram was corrected for edema: the infarct represented 31 ± 6% of the hemisphere in WT (n = 10) and 35 ± 7% of the hemisphere in HO1^−/− (n = 10) mice. Two HO1^−/− mice died, and no WT mice died.