Fig. 4.
Mechanism of NO-mediated apoptosis in PBMC from patients with AIDS. Cells were incubated in medium (106/ml) supplemented with SNAP (100 µM), SOD (200 U/ml), nicotinamide (5 mM), and/or 3 aminobenzamide (3AB, 2 mM). Percentage of viable, nonapoptotic cells was obtained as in legend to Figure 1. Mean ± SD from three different patients. *p < 0.04; **p < 0.003; NS, not significant indicate statistical analysis between cells treated (+) or not (−) with SOD, nicotinamide, or 3AB.