Critical Role of Nitric Oxide During the Apoptosis of Peripheral Blood Leukocytes from Patients with AIDS

Table 1 Correlation between patient in vivo parameters and plasma TNF-α and nitrite content^a

Patient	Age	CD4/mm^3a	Viral load RNA/ml^a	TNF-α (pg/ml)^a	Nitrites (µM)^a
P1^b	38	185	<200	46	7.9
P2	53	487	2801	32	7.9
P3	45	350	33414	0	9.3
P4	44	257	<200	6	7.1
P5	41	785	<200	37	4.8
P6	39	301	337	10	3.1
P7	40	134	<200	0	34.8
P8	41	404	447	0	7.0
P9	48	235	2810	19	33.7
P10	38	158	<200	0	14.6
P12	52	291	<200	9	7.3
P13*	31	400	1594	27	NT
P20	52	254	<200	389	33.8
P21	76	132	12022	373	18.2
P22	41	350	<200	749	1.1
P23	38	158	<200	11	6.4
P24	52	231	645	862	5.5
W11	43	341	<200	9	30.2
W14	48	307	2169	31	14.4
W15	59	568	<200	0	19.2
W16*	55	284	<200	0	7.1
W17	52	NT	<200	13	20.8
W18	48	113	1903	0	<1.0
W19*	31	468	2553	230	14.8
W25	53	395	2801	35	21.7
W26	36	515	<200	25	<1.0
W27	52	284	<200	502	11.7
W28	39	162	1017	286	4.2
W29	38	343	246	23	42.6
W30*	45	581	44129	19	5.5
W31	34	244	43207	802	<1.0
W32	46	530	<200	18	4.1
W33	37	59	14031	0	8.6
W34	46	193	<200	0	<1.0
W35	25	412	<200	206	11.5

^aPatients with AIDS received HAART for >7 months. Various parameters were analyzed simultaneously (see Materials and Methods for more details).
^bPatients undergoing apoptosis analysis are numbered first with P, and those analyzed only for serum factors are numbered W. Females are designated with an asterisk.

ISSN: 1528-3658