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Table 1 Influenza virus shedding during sub-lethal infection in wild type C57BL/6 and SAP knockout mice

From: Influenza Virus Infection is not Affected by Serum Amyloid P Component

Virus Titer in Nasal Washings (TC (ID50/ml))

Mouse no.

Day 3

Day 4

Day 5

Day 6

Day 7

Mean

  

Gp 1 SAP knockouts

   

1

4.3

ND

ND

ND

ND

 

2

3.5

ND

ND

ND

ND

 

3

3.7

3.4

2.2

2.0

0.5

2.36

4

3.6

1.6

1.0

3.0

1.8

2.20

5

3.0

2.6

0.5

2.8

0.5

1.88

6

4.4

2.8

1.9

1.1

1.9

2.42

7

3.7

1.7

3.6

2.2

0.5

2.34

Mean

3.74

2.42

1.84

2.22

1.04

2.24

  

Gp 2 C57BL/6 wild type

   

1

2.2

2.9

2.8

1.9

1.8

2.32

2

2.8

1.5

2.8

2.2

2.7

2.40

3

3.5

2.8

0.5

2.7

0.5

2.00

4

2.3

3.0

2.0

2.7

1.7

2.34

5

2.8

2.1

2.5

1.3

2.6

2.26

6

3.7

2.8

3.0

1.2

0.5

2.24

7

3.4

2.6

2.6

1.2

1.7

2.30

8

3.4

3.3

2.0

1.7

1.6

2.40

9

2.2

2.7

1.8

1.6

1.6

1.98

10

2.1

1.7

2.9

1.8

2.3

2.24

Mean

2.84

2.54

2.29

1.83

1.7

2.25

  1. Mice were infected intra-nasally on day 0 with the A/Shanghai/24/90 strain of influenza virus. Virus shedding was measured by titration of nasal washings taken daily as shown.