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Table 3 The level of IGF-II peptide in cell growth medium and number of IGF-I receptors on cultured lung cancer cells

From: Insulin-Like Growth Factor Family and Combined Antisense Approach in Therapy of Lung Carcinoma

 

IGF-II (ng/2 × 106 Cells)*

IGF-IR Bmax(fmo1/2 × 106 Cells)*

Cell Type

Day 5

Day 25

Day 5

Day 25

AC, case # 7

323.3 ± 37.9

34.7 ± 11.6

210.7 ± 18.8

24.3 ± 17.2

SCC, case # 62

231.3 ± 33.6

214.7 ± 19.6

180.0 ± 26.9

66.0 ± 16.5

SCC, case # 33

7.0 ± 2.0

4.0 ± 3.6

60.0 ± 18.7

13.7 ± 2.0

  1. *Values are the mean ± SD of three independent experiments (in all cases statistically different from control values obtained with cells #33).
  2. IGF-II/IGF-IR mRNA negative cells.