Table 2 Covariance analysis (ANCOVA) among genotypes and by BMI classes for the +2138InsCAGACC polymorphism of the MC3R gene in QFS. Means ± standard error and number of subjects (between parentheses) are shown for insertion (Ins) and wild-type (wt) alleles

FAT

24.0 ± 1.1

19.3 ± 0.9

20.5 ± 0.8

0.0005**

27.0 ± 1.2

31.4 ± 0.8

30.9 ± 0.7

0.002*

38.1 ± 2.0

41.1 ± 0.9

41.0 ± 0.7

0.35

(%)

(23)

(135)

(156)

(11)

(60)

(97)

(7)

(56)

(69)

FM

15.7 ± 0.9

11.7 ± 0.7

12.6 ± 0.6

0.0003**

18.3 ± 1.0

22.8 ± 0.8

22.0 ± 0.6

0.0001**

44.8 ± 3.9

49.6 ± 1.6

48.4 ± 1.2

0.42

(kg)

(23)

(135)

(156)

(11)

(60)

(97)

(7)

(56)

(69)

BMI

22.1 ± 0.4

21.6 ± 0.2

21.9 ± 0.2

0.18

26.3 ± 0.3

27.6 ± 0.2

27.3 ± 0.1

0.004

37.8 ± 2.2

40.5 ± 1.5

40.9 ± 1.5

0.27

(kg/m²)

(27)

(152)

(188)

(11)

(74)

(117)

(7)

(75)

(97)

RQ

0.805 ± 0.014

0.812 ± 0.006

0.806 ± 0.006

0.53

0.826 ± 0.012

0.829 ± 0.008

0.804± 0.005

0.009

0.774 ± 0.014

0.786 ± 0.009

0.795 ± 0.009

0.91

(24)

(141)

(171)

(11)

(66)

(102)

(7)

(63)

(74)

INT

9622 ± 334

9665 ± 214

9468 ± 238

0.70

11681 ± 1029

10954± 417

9878± 254

0.03

10672 ± 898

10284± 690

11057 ± 705

0.14

(kj)

(24)

(140)

(173)

(11)

(64)

(107)

(7)

(62)

(87)

ATF

253 ± 12

238 ± 8

245 ± 8

0.33

367 ± 24

391 ± 13

385 ± 12

0.58

595 ± 24

694± 21

706 ± 25

0.002*

(mm)

(16)

(99)

(137)

(10)

(57)

(84)

(7)

(52)

(57)

ASF

186 ± 10

163 ± 6

170 ± 6

0.08

274 ± 21

285 ± 9

276± 8

0.51

401± 26

510 ± 18

505 ± 22

0.008

(mm)

(16)

(99)

(137)

(10)

(57)

(84)

(7)

(52)

(57)