Table 2B Common sequence motifs B localized in TMS4 in the mycobacterial drug efflux transporters.
Predominant Residue at Position | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | |
Sequence | L | X | X | X | R | X | X | Q | G | X | G | A | A |
Rv0037c | G | D | V | P | L | L | V | G | A | L | V | A | N |
Rv0191 | L | A | A | G | R | V | L | C | A | V | T | H | G |
Rv0783c | L | I | I | F | R | V | V | Q | G | F | G | G | G |
Rv0849 | V | L | I | A | A | A | A | T | G | F | A | G | A |
Rv1250 | L | I | A | A | R | V | V | Q | G | V | G | A | G |
Rv1258c | N | V | L | V | L | A | V | L | A | A | L | A | A |
Rv1410c | L | I | A | G | R | T | I | Q | G | V | A | S | G |
Rv1634 | L | V | A | G | R | T | L | Q | G | I | A | G | G |
Rv1877 | L | A | I | S | R | A | L | Q | G | V | G | A | G |
Rv2333c | L | T | T | A | R | G | A | Q | G | L | G | A | A |
Rv2456c | I | S | V | L | Q | A | V | T | G | I | A | S | S |
Rv2459 | F | T | V | A | R | V | I | Q | G | L | G | A | A |
Rv2846c | L | V | I | A | R | L | S | Q | G | V | G | S | A |
Rv2994 | I | G | V | F | L | F | L | G | G | M | A | A | G |
Rv3239c | L | V | A | F | R | V | L | Q | G | I | G | A | A |
Rv3728 | L | V | A | F | R | V | L | Q | G | I | G | A | A |
Consensus | L | V | A | A | R | [VA] | [LV] | Q | G | [VI] | G | A | [GA] |