Fig. 2
From: Adenoviral-Induced Islet Cell Cytotoxicity Is Not Counteracted by Bcl-2 Overexpression
Cytokine-induced cell death and the effect of Bcl-2 expression in RINm5F cells (a) and pancreatic islet cells (b). Transduced (13 PFU/cell) and nontransduced cells were exposed for 1 day (RINm5F cells) or 6 days (islet cells) to the combination IL-1β (25 U/ml), TNF-α (1000 U/ml), and IFN-γ (1000 U/ml) followed by staining with bisbenzimide/propidium iodide and fluorescence microscopy. Results are mean ± SEM for four separate experiments. ***p < 0.001 when comparing versus nontransduced and nontreated cells using one-way ANOVA, Bonferroni test. ###p < 0.001 versus nontransduced cytokine-treated cells using one-way ANOVA, Bonferroni test.