Table 2 Primers for mutagenesis ^a

76C→T

5 ′-CGC GTG GGT ACC TGC AAG AGC CAG-3′

499C→T

5′-CAG GAG TAT TTG GGG AAA CCT CAA CAC C-3′

517C→T

5′-GGA AAC CTC AAC ACC TGG CTT CGG AAG C-3′

518G→A

5′-CGG GGA AAC CTC AAC ACC CAG CTT CGG AAG CTG GAC GAG CAG CAG GAG TTC AGT GCC ATC AT-3′

673C→G

5-GGG CGT GGA AGT GGG AGC CAA GGA CCA G-3′

673C→T

5′-GGG CGT GGA AGT GTG AGC CAA GGA CCA G-3′

1073delA

5′-GCA CGG CAG CTT _ ACG ATG CCC ATT-3′

Selection primer^b

5′-GGA GTC TGG AGT CTC GAC GGC TCA GAT AGC-3′