Blood glucose levels of control CBA and Shb-transgenic mice. (A) Blood glucose profiles after an intravenous glucose injection of Shb-transgenic (n = 9) and CBA (n = 7) mice. Data for mean ± SEM are given. *p < 0.05 when compared with the corresponding 30-min value of CBA mice with an unpaired Student’s t-test. (B) Blood glucose profiles, as in A, in 6-month-old mice. Data for mean ± SEM for 5 experiments are shown. *p < 0.05 using an unpaired Students’ t-test when compared with the corresponding CBA value.