Fig. 2

Effect of anti-MIF on established 38C13 B cell lymphoma growth in vivo. C3H/HeN mice were administered an i.d. injection of 38C13 tumor cells and the tumor was allowed to grow to a mean weight of 50 mg before any treatment was initiated (Day 0). C3H/HeN mice were then treated with anti-MIF mAb (■), control IgG! mAb (●), or PBS (○) every 12 hr for 4 days. Tumors were measured with Vernier calipers and their weights were estimated. Data are expressed as mean ± SD (n = 5) and are representative of one experiment that was performed three times (*p < 0.05).