Fig. 8From: Inflammatory Mediators Regulate Cathepsin S in Macrophages and Microglia: A Role in Attenuating Heparan Sulfate InteractionsTime-course analysis of LPS on macrophage and microglia cathepsin S protease activity. RAW 264.7 cells were both initially cultured and treated in MSFM with 30 ng/ml LPS for various durations, and cathepsin S protease activity was measured in cell lysates (A) and in C.M. (B) utilizing the fluorogenic substrate Z-FR-AMC. Data represent mean ± SEM of representative experiment measuring E64-inhibitable cathepsin S activity.Back to article page