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Fig. 2 | Molecular Medicine

Fig. 2

From: Neurotrophic Factors Regulate Cathepsin S in Macrophages and Microglia: A Role in the Degradation of Myelin Basic Protein and Amyloid β Peptide

Fig. 2

Increased cathepsin S, B, and L mRNA after NGF treatment of macrophages and microglia for 24 hr. RAW macrophages (A, B) and N13 microglial (C, D) cells were treated for 24 hr in the presence of various doses of NGF, total RNA was isolated, and specific mRNA for cathepsins S, B, and L were detected by Northern analysis as described in Materials and Methods. Data shown in A and C are from a representative experiment; data in B and D are mean ± SEM from three independent experiments. Graphs represent densitometry of specific bands performed on phosphorimager.

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Molecular Medicine

ISSN: 1528-3658