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Fig. 3 | Molecular Medicine

Fig. 3

From: Neurotrophic Factors Regulate Cathepsin S in Macrophages and Microglia: A Role in the Degradation of Myelin Basic Protein and Amyloid β Peptide

Fig. 3

Effect of bFGF and NGF on macrophage and microglial cell line proliferation. RAW macrophages (A) and N13 microglia (B) initially plated in DMEM and serum for 18 hr at subconfluent cell densities were then serum starved for 6–8 hr followed by treatment with fresh MSFM alone (open squares), 10 ng/ml bFGF (open circles), or 1 ng/ml of bFGF in MSFM (open diamonds), 25 ng/ml of NGF in MSFM (open circles), or Dulbecco (Db) medium with 10% FBS (open triangles). After 1 or 2 days, the cells were harvested and counted as described in Materials and Methods. Data represent average of duplicate plates with calculated standard errors.

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Molecular Medicine

ISSN: 1528-3658