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Fig. 4 | Molecular Medicine

Fig. 4

From: Neurotrophic Factors Regulate Cathepsin S in Macrophages and Microglia: A Role in the Degradation of Myelin Basic Protein and Amyloid β Peptide

Fig. 4

Increased cathepsin S protease activity in cells and conditioned medium of bFGF-treated macrophages and microglia. Cells were treated for 24 hr with various doses of bFGF and cathepsin S protease activity was measured in cells (A, B), and C.M. (C, D) as described in Materials and Methods. Data represent mean ± SEM of triplicate determinations measuring the E64-inhibitable cathepsin S activity. Activity in the absence of bFGF treatment is taken as control (100%).

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