Fig. 4

Analysis of Mcl-1, p-GSK and Akt activity in betulinic acid-treated cells. Concomitant Mcl-1, phospho-GSK (p-GSK) and total (phosphorylation — state independent) Akt analysis in cells treated for 18 h with betulinic acid and/or LY29004 (each at 10 µg/ml).