Fig. 3
From: β-Lapachone Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells
Time-dependent effect of β-lapachone on cell cycle progression in SW620 cells. SW620 cells were briefly exposed to β-lapachone (5 µM) for 4 hr, incubated in drug-free medium for a total of 12, 24, 48, or 72 hr, and then analyzed for cell cycle distribution. Control cells were exposed to DMSO alone. (A) DNA histograms depicting cell cycle distribution. The apoptotic cells (Apo) in the sub-G1 population are indicated by an arrow. (B) Percentages of SW620 cells in G1, S, and G2/M phase at various times after β-lapachone treatment.