Skip to main content
Fig. 4 | Molecular Medicine

Fig. 4

From: Pharmacogenomics of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and the Cystic Fibrosis Drug CPX Using Genome Microarray Analysis

Fig. 4

Radial histogram of the effect of CPX on global gene expression of wild-type and ΔF508-CFTR-transfected cells. (a) Low-resolution radial distribution plot of CPX induced changes in gene expression. Angles are directions in orthogonal genomic space in which ratios of gene expression were changed by exposure to CPX. The radius represents numbers of genes in that category. The colors represent all genes (red); genes whose vector length is changed by <1 SD from the average (blue); genes whose vector length is changed by 1 SD from the average (yellow); genes whose vector length is changed by 1–-2 SDs (green); and those changed by more than 2 SDs (brown), (b) Higher-resolution radial distribution plot of CPX-induced changes in gene expression, (c) Highest-resolution radial distribution plot of CPX-induced changes in gene expression.

Back to article page

Molecular Medicine

ISSN: 1528-3658