Table 1 Metabolic and immunological characteristics of 16-wk-old mice
Analyte | E−/− × IL-10+/+ | E−/− × IL-10−/− | ||||||
|---|---|---|---|---|---|---|---|---|
Male | n | Female | n | Male | n | Female | n | |
Plasma proteins and lipids | ||||||||
Plasma protein (g/dL) | 4.91 ± 0.18 | 7 | 4.89 ± 0.09 | 4 | 4.85 ± 0.12 | 9 | 4.90 ± 0.11 | 5 |
Total cholesterol (mM) | 12.6 ± 1.0 | 7 | 11.1 ± 1.5 | 4 | 11.1 ± 0.7 | 9 | 8.7 ± 0.7 | 4 |
Triglycerides (mg/dL) | 1.5 ± 0.1 | 7 | 1.3 ± 0.1 | 4 | 1.4 ± 0.1 | 9 | 1.1 ± 0.1 | 4 |
Immune system status at baseline | ||||||||
Total IgG2a (AU) | 0.985 ± 0.062 | 7 | 0.879 ± 0.102 | 4 | 0.965 ± 0.114 | 9 | 1.149 ± 0.038a | 5 |
Total IgG1 (AU) | 0.515 ± 0.021 | 7 | 0.501 ± 0.035 | 4 | 0.520 ± 0.048 | 9 | 0.546 ± 0.007 | 5 |
IL-12 (pg/mL) | 60 ± 14 | 7 | 74 ± 16 | 4 | 258 ± 147b | 9 | 109 ± 31 | 5 |
IFNγ (pg/mL) | 253 ± 27 | 7 | 209 ± 96 | 4 | 320 ± 82b | 9 | 444 ± 31a | 5 |