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Fig. 3 | Molecular Medicine

Fig. 3

From: Efficient Mitochondrial Import of Newly Synthesized Ornithine Transcarbamylase (OTC) and Correction of Secondary Metabolic Alterations in spfash Mice following Gene Therapy of OTC Deficiency

Fig. 3

OTC labeling densities in mitochondria, cytosol, and nuclei. OTC labeling densities were quantified in hepatic mitochondria, cytosol, and nuclei of control C3H mice, untreated spfash mice, and spfash mice treated with either Ad.mOTC or Ad.hOTC virus. Values were obtained by evaluating at least 150 mitochondria and 150 µm2 area of nuclei and cytosol from each group. Liver OTC activities were determined by OTC lysate assay.

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Molecular Medicine

ISSN: 1528-3658