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Fig. 3 | Molecular Medicine

Fig. 3

From: Interaction of Borrelia burgdorferi with Peripheral Blood Fibrocytes, Antigen-Presenting Cells with the Potential for Connective Tissue Targeting

Fig. 3

Interaction of B. burgdorferi with peripheral blood fibrocytes.

The figures represent fibrocyte/B. burgdorferi interactions of approximately 1–2 hr. (A) Fibrocyte sectioned perpendicular to substrate and showing polarized binding of spirochetes (M297). Bar = 4 µm. (B) Periphery of fibrocyte showing uptake of spirochetes. Some of the pseudopodial profiles resemble coiled phagocytosis (asterisk). Bar = 500 nm. (C) Location of B. burgdorferi within recesses of the cell membrane, deep within the cytoplasm of a fibrocyte. Bar = 200 nm. (D) Rounded fibrocyte. The arrowheads delineate the area enlarged in (E). Bar = 2 µm. (E) Enlargement from (D), delineated area. Spirochetes are located in deep invaginations of the cell membrane, deep within the cytoplasm. Bar = 500 nm.

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Molecular Medicine

ISSN: 1528-3658