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Fig. 3 | Molecular Medicine

Fig. 3

From: Chemotherapy Cytotoxicity of Human MCF-7 and MDA-MB 231 Breast Cancer Cells Is Altered by Osteoblast-Derived Growth Factors

Fig. 3

Example of growth of MCF-7 cells in the three-dimensional type I collagen system (3-D system). (a) The 3-D system maintained MCF-7 cells. (b) Adriamycin significantly decreased the number of MCF-7 cells in the 3-D system. (c) Co-culture of MCF-7 cells with MG-63 osteoblast-like cells also decreased the number of MCF-7 cells grown in this system. (d) Adriamycin exposure further decreased the number of MCF-7 cells under these co-culture conditions. White arrows, MG-63 cells; black arrows, MCF-7 cells.

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Molecular Medicine

ISSN: 1528-3658