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Fig. 5 | Molecular Medicine

Fig. 5

From: Chemotherapy Cytotoxicity of Human MCF-7 and MDA-MB 231 Breast Cancer Cells Is Altered by Osteoblast-Derived Growth Factors

Fig. 5

Growth of MDA-MB 231 cells in the three-dimensional type I collagen system (3-D system). (a) The 3-D system maintained MDA-MB 231 cells. (b) Adriamycin significantly decreased the number of MDA-MB 231 cells in the 3-D system. (c) Co-culture of MDA-MB 231 cells with MG-63 osteoblast-like cells increased the number of MCF-7 cells. (d) Adriamycin exposure did not significantly affect the number of MDA-MB 231 cells when co-cultured with MG-63 cells.

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Molecular Medicine

ISSN: 1528-3658