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Fig. 1 | Molecular Medicine

Fig. 1

From: A Chimeric Mouse Model of Gaucher Disease

Fig. 1

Spleen and peripheral blood leukocyte acid β-glucosidase activity of irradiated mice reconstitution after transplantation with hematopoietic stem cells from a fetus homozygous for targeted disruption of the glucocerebrosidase gene (KO-1 and KO-2) or homozygous wild-type fetus hematopoietic stem cells (control) at various time periods after transplantation. Liver acid β-glucosidase activity was essentially normal (data not shown). This is the expected finding, because hepatocytes are of host type.

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Molecular Medicine

ISSN: 1528-3658