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Fig. 4 | Molecular Medicine

Fig. 4

From: The Role of Salt Bridge Formation in Glucagon: An Experimental and Theoretical Study of Glucagon Analogs and Peptide Fragments of Glucagon

Fig. 4

(A) A conformation of a tetrapeptide fragment derived from glucagon representing residues 9–12: Asp9-Tyr10-Ser11-Lys12, featuring a hydrogen bond between the hydrogen of the β-carboxyl group of Asp9 and the lone pair of electrons on ε-amino group of Lys12. (B) An extended conformation of the tetrapeptide in Figure 4A. (C) A coiled conformation of the tetrapeptide in Figure 4A, featuring a hydrogen bond between a hydrogen in Lys12 and a backbone oxygen.

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Molecular Medicine

ISSN: 1528-3658