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Fig. 6 | Molecular Medicine

Fig. 6

From: Poly(ADP-ribose) Polymerase is a Regulator of Chemokine Production: Relevance for the Pathogenesis of Shock and Inflammation

Fig. 6

Colonic MIP-1α levels, body weight loss, histologic severity score, colon length, colonic MPO and MDA levels in control and DSS-colitic mice in the presence or absence of treatment with the PARP inhibitor PJ34 (10 mg/kg/day). *p < 0.05 represents significant increase in the various parameters after DSS colitis and in #p < 0.05 represents significant inhibition by PJ34 during colitis. Each bar represents data from n = 7–9 animals.

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Molecular Medicine

ISSN: 1528-3658